Custom Membrane Protein Production
Membrane proteins play an essential role in life activities. In the sequenced genome, membrane proteins account for 30% of drug-targeted sites. Functions such as signal transmission between cells and detection of the external environment are mostly realized through special membrane receptor proteins on biological membranes. Many human diseases are related to the abnormal function of these membrane proteins. Membrane proteins are important drug targets, but their application is limited due to factors such as low expression, difficulty in preparation, and poor stability. With a professional membrane protein production team and rich experience in membrane protein production, Creative Biostructure can express and purify membrane proteins that are currently unavailable in the market (such as GPCRs, ion channels, transporters, enzymes, and viral targets).
What Membrane Proteins Can We Produce?
We can express but are not limited to the following membrane proteins:
| Monotypic/Peripheral Protein Production | ||
| Alpha/Beta-Hydrolase | FYVE/PHD Zinc Finger Protein | Phosphatidylinositol 3-/4-Kinase |
| Annexins | Galactose-Binding Domain-Like Protein | PLC-like Phosphodiesterase |
| Bet V1-Like Protein | Glycolipid Transfer Protein | Phosphotyrosine Protein Phosphatases II |
| C1 Domain-Containing Protein | Immunoglobulin-Like Superfamily (E Set) Protein | P-Loop Containing Nucleoside Triphosphate Hydrolase |
| C2 Domain-containing Protein | Lipocalin | Protein kinase superfamily |
| CoA-Dependent Acyltransferases | Lipoxygenase | PX Domain-Containing Protein |
| CRAL-TRIO Domain-Containing Protein | PGBD superfamily | Saposin |
| PH Domain-Like Protein | Synuclein | DNase I-like protein |
| Fibrinogen | Transcriptional factor tubby | |
| Membrane Protein Peptides Production | ||
| Amyloid Beta-sheet Peptides | Peptide Fragments of Transmembrane Protein | Peptide fragments of water-soluble proteins |
| Membrane Anchor Helices of Peripheral Proteins | ||
Advantages of Our Membrane Protein Production Service
Creative Biostructure has rich experience in membrane protein research, and the advantages of our service include the following:
- Short Experimental Period: With optimized procedures, we can deliver the membrane proteins required by customers in the shortest time.
- Various Expression Systems: We have a variety of membrane protein expression systems, and the most suitable system can be selected according to the needs of customers for the production of membrane proteins.
- High Activity: Our platform enables membrane proteins to be crystallized while maintaining their native conformation and retaining their function and activity.
- One-Stop Service: We provide one-stop membrane protein production services and can also offer membrane protein crystallization and cryo-electron microscopy services.
Creative Biostructure's scientists will assist you in all project stages of evaluation, planning, and execution. Each project is tailored to the customer's specifications of scale, purity, analytical characterization, and activity. We help our customers plan their projects in the most cost-efficient manner. Please feel free to contact us for a detailed quote.
Ordering Process
