Liposomes for Cosmetics

Consumers are more focused on their health and appearance than ever before. This trend creates an increasing demand for functional cosmetics ingredients and efficient delivery systems. Known for high performance and efficient development in liposome delivery systems, Creative Biostructure has extended the applications into the cosmetic industry.

Why use liposomes in cosmetics?

Liposomes are most widely known as spherical vesicles composed of phospholipids with an aqueous core that can be used as the delivery vehicle. For example, some studies suggested that liposomes facilitate the passage of active ingredient across the stratum corneum and transport them to the deep layers of the epidermis where they are absorbed and needed most. Liposomes is not only an effective tool to help skin absorb active cosmetic ingredients, but also improve the stability of active ingredients, increase skin hydration by surface adhesiveness, enhance dermal bioavailability and skin targeting, and protect skin cells for external stressor, such as sun or sweat. Nowadays, those properties of liposomes have been already used in cosmetic products such as moisturizers, hair shampoos, creams, lotions, etc., resulting in a revolutionary uplift of cosmetic industry.

Figure 1. Smaller liposomes have been more effective in delivery of active cosmetic ingredients. (Advanced Drug Delivery Reviews, 2008)

Creative Biostructure offers both products and services to support cosmetic formulation development, which are endorsed by the market for several unique advantages:

• Ready-to-use cosmetic liposome products. Encapsulation of coenzyme Q10, astaxanthin, alpha lipoic acid, vitamin C and so on.
• Liposome manufacturing in bioactive and cosmetic grade.
• Custom manufacturing with particular properties, such as high temperature stable, pH stable, oxidation resisting, and stealth liposomes.
• Manufacturing of nano liposomes. Various sizes (30 to 70 nanometers) and production scales (mL to large scale) are available.

Creative Biostructure is committed to worry-free and case-specific services for development of functional ingredients and innovative delivery systems. We look forward to working with you to deliver health and beauty products. For more information, please contact us.

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References

1. V. B. Patravale, S. D. Mandawgade. (2013) Novel cosmetic delivery systems: an application update. International Journal of Cosmetic Science, 30, 19-33.
2. R.H. Müller, R.D. Petersen, A. Hommoss et al. (2007) Nanostructured lipid carriers (NLC) in cosmetic dermal products. Advanced Drug Delivery Reviews. 59: 522-530.
3. Gabriele Betz, Angela Aeppli, Natalia Menshutina, et al. (2005). In vivo comparison of various liposome formulations for cosmetic application. International Journal of Pharmaceutics. 296:44-54.