MicroED for New Material Analysis

In the study of Metal-organic frameworks (MOFs)/ Conjugated organic frameworks (COFs), the slowest step is often the determination of the structure of the product. Now we can use MicroED for structural analysis, and we can collect data and analyze the structure of 100 nm single crystal samples. Nano-sized crystal culture is much less difficult for you. For many difficult MOFs, the single crystal culture cycle time has also been reduced from weeks to 1 day or even a few hours. Especially for COFs that are more difficult to perform single-crystal culture, there are already several COFs with unknown structures, and accurate structures have been obtained by MicroED.

Figure 1. MicroED testing process.

Applications

The researchers have photochemically active MOFs (PCN-415 and PCN-416) for the structure resolution. The structures of these two MOFs, which have very small crystal particles (only 500 nm), were obtained by using MicroED and were further confirmed by Rietveld refinement of the powder X-ray diffraction data.

Figure 2. Coordination compounds based on [Ti₈Zr₂O₁₂(RCOO)₁₆] cluster. (Shuai, Y., et al., 2018)

Creative Biostructure specializes in MicroED technology and has a leading MicroED test platform that can quickly and accurately analyze the structure of nanocrystals and obtain structural information without the need for a long period in single crystal culture, providing technical support for the academic research community. In addition, MicroED can further test proteins, peptides, small molecules, and other materials. Please contact our staff to discuss your project requirements.

Ordering Process

Reference

1. Yuan S, et al. [Ti₈Zr₂O₁₂ (COO) ₁₆] Cluster: an ideal inorganic building unit for photoactive metal–organic frameworks. ACS Central Science. 2018. 4(1): 105-111.