DSPE-PEG-DBCO(Lipo-521)
| Product Summary | |
|---|---|
| Name | DSPE-PEG-DBCO |
Download Datasheet
|
|
| Cat No. | Lipo-521 |
| Product Overview | 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol with dibenzocycolctyne (DSPE-PEG-DBCO) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and an DBCO for Cu-free chemistry. DSPE derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole product without the need for a toxic catalystPEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. |
| Purity | >95% |
| Application | Liposome production; Synthetic lipid |
| Synonyms | 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-poly(ethylene glycol)-dibenzocycolctyne |
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Frequently Asked Questions
-
Can you provide information on the size and composition of your liposomes?
Yes, we offer detailed specifications for each product, enabling researchers to select liposomes that best match their experimental requirements.
-
Do you offer customization options for liposome formulations?
Yes, we offer customization services to meet the unique demands of research projects. Our team of experts can work with customers to develop custom liposome formulations tailored to their specific needs, ensuring optimal results for their experiments.
-
What analytical and characterization data do you provide with your liposome products?
We provide comprehensive analytical and characterization data for all our liposome products, such as size distribution, zeta potential, and encapsulation efficiency.
