NTF3 with NGFR Protein Crystal(CBCRY18)
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| Product Summary | |
|---|---|
| Name | NTF3 with NGFR Protein Crystal |
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| Cat No. | CBCRY18 |
| Fragment | Ectodomain |
| Protein Description | Neurotrophin-3 complexed with NTR receptor |
| Background | Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT. |
| Protein Classification | signaling protein |
| Structure Weight | 63861.22 Da |
| Method | X-Ray Diffraction |
| Resolution | 2.6Å |
| Ligand Chemical Component | N-Acetyl-D-Glucosamine |
| Reference | Gong, Y., Cao, P., Yu, H.J., Jiang, T. (2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature 454: 789-793 |
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