EphA2 Protein Crystal(CBCRY49)
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| Product Summary | |
|---|---|
| Name | EphA2 Protein Crystal |
Download Datasheet
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| Cat No. | CBCRY49 |
| Fragment | Ectodomain, Residues 27-534 |
| Protein Description | EPH Receptor A2 |
| Background | Ephrin type-A receptor 2 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. It regulates cell adhesion and differentiation and also participates in UV radiation-induced apoptosis. Mutations in this gene are the cause of certain genetically-related cataract disorders. |
| Protein Classification | Receptor |
| Structure Weight | 60679.26 Da |
| Method | X-Ray Diffraction |
| Resolution | 3.00 Å |
| Ligand Chemical Component | Cl-, NAG |
| Reference | Seiradake E, Harlos K, Sutton G, Aricescu AR, Jones EY. An extracellular steric seeding mechanism for eph- ephrin signalling platform assembly. Nat.Struct.Mol.Biol. (2010) 17 p.398 |
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