DAAO Protein Crystal(CBCRY46)
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Product Summary | |
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Name | DAAO Protein Crystal |
Download Datasheet | |
Cat No. | CBCRY46 |
Fragment | Full length |
Protein Description | D-amino Acid Oxidase 3 |
Background | This gene encodes the peroxisomal enzyme D-amino acid oxidase. The D-amino acid oxidase is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. It regulates the level of the neuromodulator D-serine in the brain, has high activity towards D-DOPA and contributes to dopamine synthesis. |
Protein Classification | Oxidoreductase |
Structure Weight | 161715.92 Da |
Method | X-Ray Diffraction |
Resolution | 2.50 Å |
Ligand Chemical Component | BEZ, FAD |
Reference | Kawazoe T, Tsuge H, Pilone MS, Fukui K. Crystal structure of human d-amino acid oxidase: context-dependent variability of the backbone conformation of the vaagl hydrophobic stretch located at the si-face of the flavin ring. Protein Sci. (2006) 15 p.2708 |
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