ARTN Protein Crystal(CBCRY32)
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| Product Summary | |
|---|---|
| Name | ARTN Protein Crystal |
Download Datasheet
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| Cat No. | CBCRY32 |
| Fragment | N-terminal truncated |
| Protein Description | Neurotrophic Factor Artemin Isoform 3 |
| Background | Artemin (ARTN) is a member of the glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) which regulate the development and maintenance of many neuronal populations in the mammalian nervous system. Here we report the 1.92 A crystal structure of the complex formed between ARTN and its receptor GFRalpha3, which is the initiating step in the formation of a ternary signaling complex containing the shared RET. |
| Protein Classification | Hormone/growth Factor |
| Structure Weight | 11574.40 Da |
| Method | X-Ray Diffraction |
| Resolution | 1.76Å |
| Reference | Wang, X., Baloh, R.H., Milbrandt, J., Garcia, K.C. (2006) Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors. Structure 14: 1083-1092 |
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