FlexipolyLiposome Service

FlexipolyLiposome is a liposomal nanoparticle developed by Creative Biostructure, adopting a highly tunable liposome structure that provides significant advantages in drug delivery. In comparison to traditional liposomes, the stability of FlexipolyLiposome is markedly improved. It not only maintains stability throughout the drug delivery process but also demonstrates practicality in various detections, making it suitable for applications in protein functional research, drug development, and drug delivery.

What is FlexipolyLiposome?

Liposomes, also known as hollow liposomes, are artificial membrane structures composed of lipids such as lecithin and ceramide. Their bilayer structure closely resembles that of skin cell membranes. In water, the hydrophilic heads of the phospholipid molecules extend into the water while their hydrophobic tails point toward the air. Through stirring, these lipid molecules form spherical liposomes with diameters ranging from 25 to 1000 nanometers. Liposomes have essential applications in drug delivery and gene therapy, serving as drug carriers that utilize their fusion properties with cell membranes to deliver drugs into cells. Polymeric liposomes, a novel nanocarrier system consisting of polymers and lipids with excellent biocompatibility and biodegradability, can encapsulate and deliver insoluble drugs. Their core comprises a water-soluble polymer wrapped in a hydrophobic lipid layer, ensuring stable drug packaging and controlled release within the body. Polymeric liposomes hold promising applications in drug delivery, particularly for low water-soluble drugs, offering treatment options for tumors, inflammation, infection, and various diseases, with adjustable properties to meet diverse drug requirements.

Creative Biostructure is dedicated to developing liposome products with enhanced performance. FlexipolyLiposome, a polymeric liposome product, effectively extends stability and can be used in the pharmaceutical field to create efficient delivery systems, including targeted delivery, sustained-release delivery, and controlled-release delivery. This product, with its highly adjustable liposome structure, ensures excellent drug stability and delivery efficiency, making it suitable for various detection assays such as SPR, pull-down, CO-IP, etc.

Figure 1. Polymer/polyelectrolyte-Liposome Complex. (Jephcott L, et al., 2021)

What are the Advantages of FlexipolyLiposome?

• Good Biocompatibility: FlexipolyLiposome, composed of natural or synthetic polymers and lipids, exhibits excellent compatibility with organisms, reducing adverse reactions to the human body.
• Prolonged Stability: FlexipolyLiposome protects sensitive drugs from clearance or degradation in the blood, extending the drug's life cycle.
• Controlled Release: The release rate of the drug can be controlled through different preparation methods and component ratios, achieving sustained or progressive drug release.
• Targeted Delivery: By modifying the surface or coating it with specific ligands, FlexipolyLiposome enables targeted drug delivery, enhancing the therapeutic effect and reducing damage to healthy cells.

Highlights of Our FlexipolyLiposome Service

• Comprehensive Expertise in FlexipolyLiposome Technology: Our specialized team possesses in-depth insights into the intricacies of FlexipolyLiposome technology, ensuring unparalleled quality and reliability in our services.
• Cost-Effective Solutions for Precise Outcomes: Our FlexipolyLiposome service provides highly accurate results at a competitive price, offering a cost-effective approach to meet your research objectives. Maximize the efficiency of your budget while obtaining reliable and precise data.
• Integrated Solutions for Seamless Workflow: Enjoy a one-stop experience with our services, covering everything from formulation development to targeted delivery systems.
• Customizable Solutions Tailored to Your Needs: Our services are flexible and can be customized to suit your specific requirements. Whether you need tailored formulations or unique delivery strategies, we adapt our services to meet the unique demands of your research projects.

Creative Biostructure has rich experience in liposome research, and we provide high-quality liposomes, modification and functional research, and tailor-made research solutions for customers to meet specific needs. Please feel free to contact us for a detailed quote if you're interested in our services.

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Reference

1. Jephcott L, et al. A conjugated polymer‐liposome complex: A contiguous water‐stable, electronic, and optical interface. View. 2021, 2(1): 20200081.