2D SPR Microarray Development

Creative Biostructure is a leader in the development of two-dimensional surface plasmon resonance (2D SPR) microarrays, delivering innovative solutions for biomedical research and diagnostics. Our technology harnesses plasmonic resonances for real-time, label-free monitoring of biomolecular interactions. We provide personalized microarray services to cater to our client's unique requirements, boosting research effectiveness across various fields.

What are 2D SPR Microarrays?

2D SPR microarrays are advanced tools for tracking biomolecular interactions without needing labels. They work by sensing changes in light reflection caused by biomolecules binding to the microarray surface. This technology is a big help in medical research and testing. It can measure different kinds of biomolecular interactions, like how proteins connect with other proteins, DNA, or small molecules. The information it provides is key to decoding complicated biological activities.

Technical Advantages of 2D SPR Microarrays

• Enhanced Multiplexing: Enables the simultaneous analysis of multiple interactions on a single chip.
• Real-time Analysis: Allows for real-time monitoring of interaction dynamics without the need for labels.
• Increased Sensitivity: Offers improved detection limits for precise quantification of molecular interactions.
• Customizable Designs: Provides tailored microarray layouts to meet specific experimental requirements.
• High Throughput Screening: Facilitates accelerated data generation and analysis for efficient research workflows.

Applicable Fields of 2D SPR Microarrays

2D SPR microarrays have applications in a wide range of fields, including:

• Drug Discovery: Used for screening drug candidates and evaluating drug-target interactions.
• Biomedical Research: Employed in the study of protein-protein interactions and biomolecular recognition processes.
• Diagnostic Development: Assists in the development of sensitive and specific diagnostic assays for disease detection.
• Biotechnology: Aids in the characterization of biotherapeutics and optimization of bioprocesses.
• Environmental Monitoring: Detects specific pathogens or contaminants in water and air samples.

Figure 1. 2D SPR microarrays. (Creative Biostructure)

Our 2D SPR Microarray Development Services

• Custom Microarray Design

We provide bespoke microarray design services that cater to specific research goals. By collaborating closely with clients, we can develop tailored microarrays featuring desired biomolecules, ensuring optimal performance for targeted applications. This includes selecting the appropriate coupling chemistry and surface functionalization strategies to enhance detection capabilities.

• Comprehensive Data Analysis

We also deliver comprehensive data analysis. By employing advanced algorithms and specialized software, we ensure that the data yield actionable insights into biomolecular interactions. Clients receive detailed reports that include interaction kinetics, binding affinities, and informative visualizations.

• Quality Control and Assurance

All microarray products undergo rigorous quality control protocols. We utilize stringent testing methods to assess the performance characteristics of each array prior to deployment. These protocols include assessing the specificity and sensitivity of the arrays under various experimental conditions to guarantee reliable results.

Our Service Process for Developing 2D SPR Microarrays

1. Consultation: We hold initial discussions with the client to understand the project goals and requirements, ensuring that the design and development process perfectly aligns with the client's research objectives.
2. Design Phase: We initiate the microarray development phase based on the customer's specifications, including design optimization, surface functionalization, and testing.
3. Chip Fabrication: We precisely fabricate 2D SPR microarrays using advanced lithography techniques and high-quality materials.
4. Analytical Development: We optimize analytical conditions to achieve accurate and reproducible results.
5. Data Analysis: We conduct thorough analysis and interpretation of data to extract valuable insights.
6. Report Generation: We provide a comprehensive analytical report, covering the chip fabrication process, analytical results, and their scientific interpretation.

Why Choose Creative Biostructure?

• Advanced Technology: Our cutting-edge SPR technology offers real-time monitoring of biomolecular interactions, delivering high sensitivity and specificity. This ensures that the data collected for your research is accurate and reliable.
• Tailored Solutions: Recognizing the uniqueness of each research project, we offer fully customizable services. You have the flexibility to define the specific interactions you wish to investigate and the conditions for your experiments, allowing us to tailor our approach to your exact requirements.
• Quick Results: Our commitment to efficiency and advanced methodologies means we can deliver your microarray solutions quickly. We prioritize speed without sacrificing the quality of our work.
• All-Encompassing Assistance: From the initial consultation to the interpretation of results, we offer comprehensive support. Our team of scientists collaborates closely with you to ensure that your project objectives are achieved and that you overcome any research challenges effectively.

Frequently Asked Questions

• What are the primary research applications of your 2D SPR microarray technology?

  Our 2D SPR microarray technology is versatile, with key applications in drug discovery, diagnostics, and environmental monitoring. It enables real-time observation of molecular binding kinetics and affinities, detects biomarkers, and identifies pathogens and contaminants.

• What is the typical turnaround time for a 2D SPR microarray project?

  The turnaround time depends on the project's complexity and customization level. We provide timelines during the consultation phase and strive to meet client deadlines.

• What support do you provide during and after the service?

  We provide full support, from helping you plan your experiment, giving you a hand while you do it, to analyzing your data once it's done.

Creative Biostructure makes custom 2D SPR microarrays just for you and your work. Want to know more about how we can develop these microarrays for you? please contact us. Our experts are here to help you with new ideas to push your research forward.

Ordering Process

References

1. Singh S, Singh P K, Umar A, et al. 2D nanomaterial-based surface plasmon resonance sensors for biosensing applications. Micromachines. 2020. 11(8): 779.
2. Su Y, Wang W. Surface plasmon resonance sensing: from purified biomolecules to intact cells. Analytical and Bioanalytical Chemistry. 2018. 410: 3943-3951.
3. Wang D, Loo J F C, Lin W, et al. Development of a sensitive DMD-based 2D SPR sensor array using single-point detection strategy for multiple aptamer screening. Sensors and Actuators B: Chemical. 2020. 305: 127240.