Recent Advances in Optogenetics (II)

(…Continued)   Cell: optogenetics makes the mouse incarnate the cruel killer doi:10.1016/j.cell.2016.12.027     There is a killer hidden in every mouse. Researchers have found areas of the brain that control predatory behavior and have succeeded in finding a way to control their switches. Dr. Ivan de Araujo from Yale University and colleagues found two nerves in the brain that control the hunting behavior of mice, one coordinated to chase…

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Recent Advances in Optogenetics (I)

Optogenetics is a rapidly developing multi-disciplinary bioengineering technology that integrates optics, software control, gene manipulation technology, and electrophysiology. The main principle is to first use gene manipulation techniques to transfer light-sensitive genes (such as ChR2, eBR, NaHR3.0, Arch or OptoXR, etc.) into specific types of cells in the nervous system for expression of specific ion channels or GPCRs. The photo-sensing ion channel will selectively induce the passage of cations or…

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