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Growth of high-quality crystals is a major obstacle in many structural investigations. In recent years, the techniques for screening crystals have improved dramatically. Creative Biostructure is pioneer in the field of crystals screening, such as peptide crystallization and has led many successful campaigns to produce the crystals in small and large scale.
Besides for macromolecular structural study, a crystalline formulation has some advantages over its amorphous counterpart, including:
Creative Biostructure provides crystallization screening using a series of crystallization techniques from vapor diffusion to microbatch screening. Initial screening is conducted on a small scale using different vapor diffusion techniques (sitting drop, hanging drop, sandwich drop, and capillary) and batch crystallization techniques (slow evaporation, fast evaporation, and anti-solvent precipitation). The crystallization conditions will be further optimized and scaled up. The batch crystallization process can be applied to both small and large scale purification.
Figure 1. Collage of Crystallization Results from Small-Scale Batch Experiments
Creative Biostructure uses various leading experimental packages for advanced crystals screening and production. We are pleased to inform you the specifications for our microbatch crystallization service as follows:
Please feel free to contact us for a detailed quote.